Risk factors for hypothyroidism following hemithyroidectomy.
Ann Endocrinol (Paris)
; 84(6): 739-745, 2023 Dec.
Article
in En
| MEDLINE
| ID: mdl-37517518
ABSTRACT
OBJECTIVE:
Hypothyroidism is the most common complication of hemithyroidectomy for thyroid nodules. This retrospective cohort study investigated the prognostic factors for hypothyroidism following hemithyroidectomy.METHODS:
We included patients who underwent hemithyroidectomy between 2016 and 2017, excluding those with history of preoperative hypothyroidism or malignancy on histopathological examination. The primary endpoint was development of hypothyroidism during follow-up (TSH≥2 above normal).RESULTS:
Twenty-six of the 128 included patients (20%) developed postoperative hypothyroidism. The following independent prognostic factors were found preoperative TSH level>1.5 mIU/L (OR 2.11; P=0.013), and remaining thyroid volume adjusted for body surface area<4.0mL/m2 (OR 1.77; P=0.015). Twenty-one patients (81%) had first TSH values above the upper limit of normal. Postoperatively, first TSH level correlated significantly with the preoperative value (R=0.5779, P<0.001). Levothyroxine was prescribed to 16% of patients, with a mean dose of 0.92µg/kg/day.CONCLUSION:
Patients with TSH>1.5 mIU/or remaining thyroid volume adjusted for body surface area<4.0mL/m2 should have intensified clinical and biological follow-up in the first year after surgery.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hypothyroidism
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Ann Endocrinol (Paris)
Year:
2023
Document type:
Article
Affiliation country:
Francia