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The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern.
Zhong, Wen; Danielsson, Hanna; Brusselaers, Nele; Wackernagel, Dirk; Sjöbom, Ulrika; Sävman, Karin; Hansen Pupp, Ingrid; Ley, David; Nilsson, Anders K; Fagerberg, Linn; Uhlén, Mathias; Hellström, Ann.
Affiliation
  • Zhong W; Science for Life Laboratory, Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
  • Danielsson H; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Brusselaers N; Centre for Translational Microbiome Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Wackernagel D; Sach's Children's and Youth Hospital, Södersjukhuset, Stockholm, Sweden.
  • Sjöbom U; Centre for Translational Microbiome Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Sävman K; Global Health Institute, Antwerp University, Antwerp, Belgium.
  • Hansen Pupp I; Department of Neonatology, Karolinska University Hospital and Institute, Astrid Lindgrens Children's Hospital, Stockholm, Sweden.
  • Ley D; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Nilsson AK; Learning and Leadership for Health Care Professionals At the Institute of Health and Care Science at Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
  • Fagerberg L; Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Uhlén M; Region Västra Götaland, Dept of Neonatology, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Hellström A; Department of Pediatrics, Institute of Clinical Sciences Lund, Lund University and Skane University Hospital, Lund, Sweden.
Commun Med (Lond) ; 3(1): 107, 2023 Aug 02.
Article in En | MEDLINE | ID: mdl-37532738
Being born too early can affect a baby's health. We looked at how babies born extremely preterm, meaning more than 12 weeks earlier than a full-term baby, develop. We looked at the proteins present in their blood from the day they were born until their original due date. Our study of 182 extremely preterm babies born at different points in the pregnancy (gestational ages) found that the proteins present in their blood changed in a similar way over time. This means that the age of a baby after birth, and not how early they were born, mostly affects the proteins in their blood. These findings help us understand how extremely preterm babies develop after birth, which could lead to improvements to their healthcare during the first few weeks of their life.

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Screening_studies Language: En Journal: Commun Med (Lond) Year: 2023 Document type: Article Affiliation country: Suecia Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Screening_studies Language: En Journal: Commun Med (Lond) Year: 2023 Document type: Article Affiliation country: Suecia Country of publication: Reino Unido