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PG545 sensitizes ovarian cancer cells to PARP inhibitors through modulation of RAD51-DEK interaction.
Ray, Upasana; Thirusangu, Prabhu; Jin, Ling; Xiao, Yinan; Pathoulas, Christopher L; Staub, Julie; Erskine, Courtney L; Dredge, Keith; Hammond, Edward; Block, Matthew S; Kaufmann, Scott H; Bakkum-Gamez, Jamie N; Shridhar, Viji.
Affiliation
  • Ray U; Department of Experimental Pathology and Medicine, Mayo Clinic, Rochester, MN, USA.
  • Thirusangu P; Department of Experimental Pathology and Medicine, Mayo Clinic, Rochester, MN, USA.
  • Jin L; Department of Experimental Pathology and Medicine, Mayo Clinic, Rochester, MN, USA.
  • Xiao Y; Department of Experimental Pathology and Medicine, Mayo Clinic, Rochester, MN, USA.
  • Pathoulas CL; Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
  • Staub J; University of Connecticut Health Center-Medical School, Farmington, CT, USA.
  • Erskine CL; Department of Experimental Pathology and Medicine, Mayo Clinic, Rochester, MN, USA.
  • Dredge K; Department of Oncology, Mayo Clinic, Rochester, MN, USA.
  • Hammond E; Zucero Therapeutics, South Melbourne, VIC, Australia.
  • Block MS; Zucero Therapeutics, South Melbourne, VIC, Australia.
  • Kaufmann SH; Department of Oncology, Mayo Clinic, Rochester, MN, USA.
  • Bakkum-Gamez JN; Department of Oncology, Mayo Clinic, Rochester, MN, USA.
  • Shridhar V; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.
Oncogene ; 42(37): 2725-2736, 2023 09.
Article in En | MEDLINE | ID: mdl-37550562
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Saponins / Poly(ADP-ribose) Polymerase Inhibitors Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Saponins / Poly(ADP-ribose) Polymerase Inhibitors Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido