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Systematic characterization of therapeutic vulnerabilities in Multiple Myeloma with Amp1q reveals increased sensitivity to the combination of MCL1 and PI3K inhibitors.
Sklavenitis-Pistofidis, Romanos; Lightbody, Elizabeth D; Reidy, Mairead; Tsuji, Junko; Aranha, Michelle P; Heilpern-Mallory, Daniel; Huynh, Daisy; Chong, Stephen J F; Hackett, Liam; Haradhvala, Nicholas J; Wu, Ting; Su, Nang K; Berrios, Brianna; Alberge, Jean-Baptiste; Dutta, Ankit; Davids, Matthew S; Papaioannou, Maria; Getz, Gad; Ghobrial, Irene M; Manier, Salomon.
Affiliation
  • Sklavenitis-Pistofidis R; Harvard Medical School, Boston, MA, USA.
  • Lightbody ED; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Reidy M; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Tsuji J; Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Aranha MP; Harvard Medical School, Boston, MA, USA.
  • Heilpern-Mallory D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Huynh D; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Chong SJF; Harvard Medical School, Boston, MA, USA.
  • Hackett L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Haradhvala NJ; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Wu T; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Su NK; Harvard Medical School, Boston, MA, USA.
  • Berrios B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Alberge JB; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Dutta A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Davids MS; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.
  • Papaioannou M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Getz G; Harvard Medical School, Boston, MA, USA.
  • Ghobrial IM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Manier S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
bioRxiv ; 2023 Aug 03.
Article in En | MEDLINE | ID: mdl-37577538

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos