Malignant mesothelioma cells with characteristic intracytoplasmic vacuolization and lipids.
Diagn Cytopathol
; 51(12): E328-E331, 2023 Dec.
Article
in En
| MEDLINE
| ID: mdl-37583304
ABSTRACT
In this brief report, we described some uncommon cytomorphological features of malignant mesothelioma (MM) cells in pleural effusions. The tumor cells exhibited abundant cytoplasmic vacuolization, with presence of single or multiple eccentric nuclei in several cells. In the Giemsa-stained smear, we observed a glossy spherical material in some cells, which tested positive in Sudan III stain. In immunocytochemical analysis, tumor cells were positive for calretinin, podoplanin, epithelial membrane antigen, and methylthioadenosine phosphorylase; tumor cells were negative for BRCA1-associated protein 1, CD68, and desmin. The intracytoplasmic vacuoles were positive for adipophilin expression.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pleural Effusion
/
Pleural Effusion, Malignant
/
Mesothelioma, Malignant
/
Mesothelioma
Limits:
Humans
Language:
En
Journal:
Diagn Cytopathol
Journal subject:
PATOLOGIA
Year:
2023
Document type:
Article
Affiliation country:
Japón