Divergent Findings in the Diagnosis of ATTR-CM Using Common Cardiac Diagnostics and 99m Tc-DPD Scintigraphy.
Clin Nucl Med
; 48(10): 888-889, 2023 Oct 01.
Article
in En
| MEDLINE
| ID: mdl-37586093
ABSTRACT
ABSTRACT A 77-year-old man presented with progressive deterioration of physical capacity after successful percutaneous coronary intervention of known chronic coronary syndrome. Transthoracic echocardiography revealed hypertrophy of the left ventricle, and electrocardiogram showed low QRS voltage in all leads. 99m Tc-DPD scintigraphy was conducted to differentiate etiology such as amyloidosis and revealed increased cardiac tracer uptake in the left (grade 3) and right ventricle. Immunofixation showed no signs of paraproteinemia or Bence-Jones proteinuria. Thus, biventricular involvement of ATTR-cardiomyopathy was identified by 99m Tc-DPD scintigraphy. This approach should be considered if hypertrophic phenotype is present in patients with persistent deterioration of physical capacity not attributable to coronary artery disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Amyloidosis
/
Cardiomyopathies
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
Clin Nucl Med
Year:
2023
Document type:
Article