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Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease.
Moll, Matthew; Sordillo, Joanne E; Ghosh, Auyon J; Hayden, Lystra P; McDermott, Gregory; McGeachie, Michael J; Dahlin, Amber; Tiwari, Anshul; Manmadkar, Monica G; Abston, Eric D; Pavuluri, Chandan; Saferali, Aabida; Begum, Sofina; Ziniti, John P; Gulsvik, Amund; Bakke, Per S; Aschard, Hugues; Iribarren, Carlos; Hersh, Craig P; Sparks, Jeffrey A; Hobbs, Brian D; Lasky-Su, Jessica A; Silverman, Edwin K; Weiss, Scott T; Wu, Ann Chen; Cho, Michael H.
Affiliation
  • Moll M; Department of Medicine, Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Harvard Medical School, Boston, Mass; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass.
  • Sordillo JE; Department of Population Medicine, PRecisiOn Medicine Translational Research (PROMoTeR) Center, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Mass.
  • Ghosh AJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, SUNY Upstate Medical Center, Syracuse, NY.
  • Hayden LP; Department of Pediatrics, Division of Pulmonary Medicine, Boston Children's Hospital, Harvard Medical School, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • McDermott G; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Mass.
  • McGeachie MJ; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Dahlin A; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Tiwari A; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Manmadkar MG; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Abston ED; Department of Thoracic Surgery, Massachusetts General Hospital, Boston, Mass.
  • Pavuluri C; Department of Medicine, Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Harvard Medical School, Boston, Mass; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass.
  • Saferali A; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Begum S; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Ziniti JP; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Gulsvik A; Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Bakke PS; Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Aschard H; Department of Computational Biology, Institut Pasteur, Universit de Paris, Paris, France.
  • Iribarren C; Division of Research, Kaiser Permanente Northern California, Oakland, Calif.
  • Hersh CP; Department of Medicine, Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Harvard Medical School, Boston, Mass; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass.
  • Sparks JA; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Mass.
  • Hobbs BD; Department of Medicine, Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Harvard Medical School, Boston, Mass; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass.
  • Lasky-Su JA; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Silverman EK; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Weiss ST; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Massachusetts General Hospital, Boston, Mass.
  • Wu AC; Department of Population Medicine, PRecisiOn Medicine Translational Research (PROMoTeR) Center, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Mass.
  • Cho MH; Department of Medicine, Channing Division of Network Medicine, Division of Pulmonary and Critical Care Medicine, Harvard Medical School, Boston, Mass; Harvard Medical School, Brigham and Women's Hospital, Boston, Mass. Electronic address: remol@channing.harvard.edu.
J Allergy Clin Immunol ; 152(6): 1423-1432, 2023 12.
Article in En | MEDLINE | ID: mdl-37595761

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Pulmonary Disease, Chronic Obstructive Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Child / Humans Language: En Journal: J Allergy Clin Immunol Year: 2023 Document type: Article Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Pulmonary Disease, Chronic Obstructive Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Child / Humans Language: En Journal: J Allergy Clin Immunol Year: 2023 Document type: Article Country of publication: Estados Unidos