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An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection.
de Brito, Rory C F; Holtham, Kerry; Roser, Jessica; Saunders, Jack E; Wezel, Yvonne; Henderson, Summer; Mauch, Thekla; Sanz-Bernardo, Beatriz; Frossard, Jean-Pierre; Bernard, Matthieu; Lean, Fabian Z X; Nunez, Alejandro; Gubbins, Simon; Suárez, Nicolás M; Davison, Andrew J; Francis, Michael J; Huether, Michael; Benchaoui, Hafid; Salt, Jeremy; Fowler, Veronica L; Jarvis, Michael A; Graham, Simon P.
Affiliation
  • de Brito RCF; The Pirbright Institute, Woking, United Kingdom.
  • Holtham K; The Pirbright Institute, Woking, United Kingdom.
  • Roser J; The Vaccine Group Ltd., Plymouth, United Kingdom.
  • Saunders JE; The Pirbright Institute, Woking, United Kingdom.
  • Wezel Y; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Henderson S; The Vaccine Group Ltd., Plymouth, United Kingdom.
  • Mauch T; The Vaccine Group Ltd., Plymouth, United Kingdom.
  • Sanz-Bernardo B; The Vaccine Group Ltd., Plymouth, United Kingdom.
  • Frossard JP; ECO Animal Health, London, United Kingdom.
  • Bernard M; Virology Department, Animal and Plant Health Agency, Addlestone, United Kingdom.
  • Lean FZX; Pathology and Animal Sciences Department, Animal and Plant Health Agency, Addlestone, United Kingdom.
  • Nunez A; Pathology and Animal Sciences Department, Animal and Plant Health Agency, Addlestone, United Kingdom.
  • Gubbins S; Pathology and Animal Sciences Department, Animal and Plant Health Agency, Addlestone, United Kingdom.
  • Suárez NM; The Pirbright Institute, Woking, United Kingdom.
  • Davison AJ; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
  • Francis MJ; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.
  • Huether M; BioVacc Consulting Ltd., Amersham, United Kingdom.
  • Benchaoui H; ECO Animal Health, London, United Kingdom.
  • Salt J; ECO Animal Health, London, United Kingdom.
  • Fowler VL; The Vaccine Group Ltd., Plymouth, United Kingdom.
  • Jarvis MA; ECO Animal Health, London, United Kingdom.
  • Graham SP; The Vaccine Group Ltd., Plymouth, United Kingdom.
Front Immunol ; 14: 1201973, 2023.
Article in En | MEDLINE | ID: mdl-37600784
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Matrix Proteins / Viral Nonstructural Proteins / Porcine respiratory and reproductive syndrome virus / Porcine Reproductive and Respiratory Syndrome / Herpesvirus Vaccines / Immunogenicity, Vaccine Limits: Animals Language: En Journal: Front Immunol Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Suiza
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Matrix Proteins / Viral Nonstructural Proteins / Porcine respiratory and reproductive syndrome virus / Porcine Reproductive and Respiratory Syndrome / Herpesvirus Vaccines / Immunogenicity, Vaccine Limits: Animals Language: En Journal: Front Immunol Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Suiza