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PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease.
Thakore, Pratish; Yamasaki, Evan; Ali, Sher; Sanchez Solano, Alfredo; Labelle-Dumais, Cassandre; Gao, Xiao; Chaumeil, Myriam M; Gould, Douglas B; Earley, Scott.
Affiliation
  • Thakore P; Department of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System University of Nevada, Reno School of Medicine, Reno, NV 89557-0318.
  • Yamasaki E; Department of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System University of Nevada, Reno School of Medicine, Reno, NV 89557-0318.
  • Ali S; Department of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System University of Nevada, Reno School of Medicine, Reno, NV 89557-0318.
  • Sanchez Solano A; Department of Pharmacology, Center for Molecular and Cellular Signaling in the Cardiovascular System University of Nevada, Reno School of Medicine, Reno, NV 89557-0318.
  • Labelle-Dumais C; Department of Ophthalmology and Anatomy, Institute for Human Genetics, University of California San Francisco School of Medicine, San Francisco, CA 94143.
  • Gao X; Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, CA 94158.
  • Chaumeil MM; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143-0628.
  • Gould DB; Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, CA 94158.
  • Earley S; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143-0628.
Proc Natl Acad Sci U S A ; 120(35): e2306479120, 2023 08 29.
Article in En | MEDLINE | ID: mdl-37607233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Small Vessel Diseases / Neurovascular Coupling / Hyperemia Type of study: Observational_studies / Risk_factors_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Small Vessel Diseases / Neurovascular Coupling / Hyperemia Type of study: Observational_studies / Risk_factors_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Document type: Article