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Synthesis and Biological Evaluation of Novel 2-Amino-1,4-Naphthoquinone Amide-Oxime Derivatives as Potent IDO1/STAT3 Dual Inhibitors with Prospective Antitumor Effects.
Huang, Ri-Zhen; Liang, Qiao-Ling; Jing, Xiao-Teng; Wang, Ke; Zhang, Hui-Yong; Wang, Heng-Shan; Ma, Xian-Li; Wei, Jian-Hua; Zhang, Ye.
Affiliation
  • Huang RZ; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China.
  • Liang QL; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China.
  • Jing XT; State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China.
  • Wang K; Department of Chemistry & Pharmaceutical Science, Guilin Normal College, Xinyi Road 15, Guilin 541001, China.
  • Zhang HY; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China.
  • Wang HS; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China.
  • Ma XL; State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China.
  • Wei JH; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China.
  • Zhang Y; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China.
Molecules ; 28(16)2023 Aug 19.
Article in En | MEDLINE | ID: mdl-37630387
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Naphthoquinones / STAT3 Transcription Factor Type of study: Observational_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2023 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Naphthoquinones / STAT3 Transcription Factor Type of study: Observational_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2023 Document type: Article Affiliation country: China