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Busulfan induces steatosis in HepaRG cells but not in primary human hepatocytes: Possible explanations and implication for the prediction of drug-induced liver injury.
Allard, Julien; Bucher, Simon; Ferron, Pierre-Jean; Launay, Youenn; Fromenty, Bernard.
Affiliation
  • Allard J; Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
  • Bucher S; Scribe Therapeutics, Alameda, California, USA.
  • Ferron PJ; INSERM, Univ Rennes, INRAE, Institut NUMECAN (Nutrition Metabolisms and Cancer) UMR_A 1341, UMR_S 1317, Rennes, France.
  • Launay Y; INSERM, Univ Rennes, INRAE, Institut NUMECAN (Nutrition Metabolisms and Cancer) UMR_A 1341, UMR_S 1317, Rennes, France.
  • Fromenty B; INSERM, Univ Rennes, INRAE, Institut NUMECAN (Nutrition Metabolisms and Cancer) UMR_A 1341, UMR_S 1317, Rennes, France.
Fundam Clin Pharmacol ; 38(1): 152-167, 2024 Feb.
Article in En | MEDLINE | ID: mdl-37665028
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug-Related Side Effects and Adverse Reactions / Fatty Liver / Chemical and Drug Induced Liver Injury Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Fundam Clin Pharmacol Journal subject: FARMACOLOGIA Year: 2024 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug-Related Side Effects and Adverse Reactions / Fatty Liver / Chemical and Drug Induced Liver Injury Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Fundam Clin Pharmacol Journal subject: FARMACOLOGIA Year: 2024 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido