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Design, synthesis and evaluation of ursodeoxycholic acid-cinnamic acid hybrids as potential anti-inflammatory agents by inhibiting Akt/NF-κB and MAPK signaling pathways.
Li, Xiaoxue; Hu, Yue; He, Bingxin; Li, Lingyu; Tian, Yu; Xiao, Yingjie; Shang, Hai; Zou, Zhongmei.
Affiliation
  • Li X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
  • Hu Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
  • He B; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
  • Li L; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
  • Tian Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
  • Xiao Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China.
  • Shang H; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. Electronic address: hshang@implad.ac.cn.
  • Zou Z; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union M
Eur J Med Chem ; 260: 115785, 2023 Nov 15.
Article in En | MEDLINE | ID: mdl-37678142
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Proto-Oncogene Proteins c-akt Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country: China Country of publication: Francia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Proto-Oncogene Proteins c-akt Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country: China Country of publication: Francia