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KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics.
Mouti, Mai Abdel; Deng, Siwei; Pook, Martin; Malzahn, Jessica; Rendek, Aniko; Militi, Stefania; Nibhani, Reshma; Soonawalla, Zahir; Oppermann, Udo; Hwang, Chang-Il; Pauklin, Siim.
Affiliation
  • Mouti MA; Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Deng S; Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Pook M; Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Malzahn J; Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.
  • Rendek A; Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Militi S; Department of Histopathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Nibhani R; Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Soonawalla Z; Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Oppermann U; Department of Hepatobiliary and Pancreatic Surgery, Oxford University Hospitals NHS, Oxford, UK.
  • Hwang CI; Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Pauklin S; Department of Microbiology and Molecular Genetics, University of California Davis, Davis, USA.
Nat Commun ; 14(1): 5685, 2023 09 14.
Article in En | MEDLINE | ID: mdl-37709746

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreas / Pancreatic Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreas / Pancreatic Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido