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Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer.
Kitamura, Fumimasa; Semba, Takashi; Yasuda-Yoshihara, Noriko; Yamada, Kosuke; Nishimura, Akiho; Yamasaki, Juntaro; Nagano, Osamu; Yasuda, Tadahito; Yonemura, Atsuko; Tong, Yilin; Wang, Huaitao; Akiyama, Takahiko; Matsumura, Kazuki; Uemura, Norio; Itoyama, Rumi; Bu, Luke; Fu, Lingfeng; Hu, Xichen; Wei, Feng; Mima, Kosuke; Imai, Katsunori; Hayashi, Hiromitsu; Yamashita, Yo-Ichi; Miyamoto, Yuji; Baba, Hideo; Ishimoto, Takatsugu.
Affiliation
  • Kitamura F; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Semba T; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Yasuda-Yoshihara N; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Yamada K; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Nishimura A; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Yamasaki J; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Nagano O; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Yasuda T; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Yonemura A; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Tong Y; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Wang H; Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Akiyama T; Cancer Center, Promotion Headquarters, Fujita Health University, Aichi, Japan.
  • Matsumura K; Cancer Center, Promotion Headquarters, Fujita Health University, Aichi, Japan.
  • Uemura N; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Itoyama R; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Bu L; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Fu L; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Hu X; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Wei F; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Mima K; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Imai K; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Hayashi H; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Yamashita YI; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Miyamoto Y; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Baba H; Department of Gastroenterological Surgery, Graduate School of Medical Sciences, and.
  • Ishimoto T; Gastrointestinal Cancer Biology, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.
JCI Insight ; 8(20)2023 Oct 23.
Article in En | MEDLINE | ID: mdl-37733442
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma, Pancreatic Ductal / Cancer-Associated Fibroblasts Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2023 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma, Pancreatic Ductal / Cancer-Associated Fibroblasts Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2023 Document type: Article Country of publication: Estados Unidos