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A paracrine circuit of IL-1ß/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression.
Chen, Zhihong; Giotti, Bruno; Kaluzova, Milota; Vallcorba, Montse Puigdelloses; Rawat, Kavita; Price, Gabrielle; Herting, Cameron J; Pinero, Gonzalo; Cristea, Simona; Ross, James L; Ackley, James; Maximov, Victor; Szulzewsky, Frank; Thomason, Wes; Marquez-Ropero, Mar; Angione, Angelo; Nichols, Noah; Tsankova, Nadejda M; Michor, Franziska; Shayakhmetov, Dmitry M; Gutmann, David H; Tsankov, Alexander M; Hambardzumyan, Dolores.
Affiliation
  • Chen Z; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
  • Giotti B; Department of Pediatrics, AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Winship Cancer Institute, and.
  • Kaluzova M; Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Vallcorba MP; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Rawat K; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
  • Price G; Department of Pediatrics, AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Winship Cancer Institute, and.
  • Herting CJ; Department of Neurology, Rutgers University, New Brunswick, New Jersey, USA.
  • Pinero G; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
  • Cristea S; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
  • Ross JL; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
  • Ackley J; Department of Pediatrics, AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Winship Cancer Institute, and.
  • Maximov V; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
  • Szulzewsky F; Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Thomason W; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Marquez-Ropero M; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Angione A; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA.
  • Nichols N; Department of Pediatrics, AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Winship Cancer Institute, and.
  • Tsankova NM; Emory University Department of Microbiology and Immunology, Emory Vaccine Center, Atlanta, Georgia, USA.
  • Michor F; Department of Pediatrics, AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Winship Cancer Institute, and.
  • Shayakhmetov DM; Department of Pediatrics, AFLAC Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Winship Cancer Institute, and.
  • Gutmann DH; Department of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Tsankov AM; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
  • Hambardzumyan D; Department of Oncological Sciences, The Tisch Cancer Institute, Mount Sinai Icahn School of Medicine, New York, New York, USA.
J Clin Invest ; 133(22)2023 11 15.
Article in En | MEDLINE | ID: mdl-37733448

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glioblastoma / Interleukin-1beta / Receptors, Interleukin-1 Type I Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2023 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glioblastoma / Interleukin-1beta / Receptors, Interleukin-1 Type I Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2023 Document type: Article Affiliation country: Estados Unidos