Magnesium-Mediated Umpolung Carboxylation of p-Quinone Methides with CO2.
J Org Chem
; 88(20): 14640-14648, 2023 Oct 20.
Article
in En
| MEDLINE
| ID: mdl-37773013
Magnesium-mediated reductive carboxylation of p-QMs with CO2 via an Umpolung strategy has been developed, which can be used for the preparation of various aryl acetic acids. This protocol featured high atom economy, mild conditions, and operational simplicity. The creation of this Umpolung carboxylation of p-QMs will unprecedentedly extend the application of p-QMs to nucleophilic reagents.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Org Chem
Year:
2023
Document type:
Article
Affiliation country:
China
Country of publication:
Estados Unidos