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Early Alzheimer's disease pathology in human cortex involves transient cell states.
Gazestani, Vahid; Kamath, Tushar; Nadaf, Naeem M; Dougalis, Antonios; Burris, S J; Rooney, Brendan; Junkkari, Antti; Vanderburg, Charles; Pelkonen, Anssi; Gomez-Budia, Mireia; Välimäki, Nelli-Noora; Rauramaa, Tuomas; Therrien, Martine; Koivisto, Anne M; Tegtmeyer, Matthew; Herukka, Sanna-Kaisa; Abdulraouf, Abdulraouf; Marsh, Samuel E; Hiltunen, Mikko; Nehme, Ralda; Malm, Tarja; Stevens, Beth; Leinonen, Ville; Macosko, Evan Z.
Affiliation
  • Gazestani V; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Kamath T; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Graduate Program in Biophysics and Harvard/MIT MD-PhD Program, Harvard University, Cambridge, MA 02139, USA.
  • Nadaf NM; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Dougalis A; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Burris SJ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Rooney B; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA.
  • Junkkari A; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Department of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.
  • Vanderburg C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Pelkonen A; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Gomez-Budia M; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Välimäki NN; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Rauramaa T; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Department of Pathology, Kuopio University Hospital, Kuopio, Finland.
  • Therrien M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Koivisto AM; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland; Department of Neurosciences, University of Helsinki, Helsinki, Finland; Depart
  • Tegtmeyer M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Herukka SK; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
  • Abdulraouf A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Marsh SE; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA 02115, USA.
  • Hiltunen M; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Nehme R; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Malm T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
  • Stevens B; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA 02115, USA; Howard Hughes Medical Institute (HHMI), Boston, MA 02115, USA.
  • Leinonen V; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Department of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.
  • Macosko EZ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Massachusetts General Hospital, Department of Psychiatry, Boston, MA 02114, USA. Electronic address: emacosko@broadinstitute.org.
Cell ; 186(20): 4438-4453.e23, 2023 09 28.
Article in En | MEDLINE | ID: mdl-37774681
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Alzheimer Disease / Frontal Lobe / Neurons Limits: Humans Language: En Journal: Cell Year: 2023 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Alzheimer Disease / Frontal Lobe / Neurons Limits: Humans Language: En Journal: Cell Year: 2023 Document type: Article Affiliation country: Estados Unidos