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Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.
Mersal, Karim I; Abdel-Maksoud, Mohammed S; Ali, Eslam M H; Ammar, Usama M; Zaraei, Seyed-Omar; Haque, Md Mamunul; Das, Tanuza; Hassan, Noha F; Kim, Eunice EunKyeong; Lee, Jun-Seok; Park, HaJeung; Lee, Kwan Hyi; El-Gamal, Mohammed I; Kim, Hee-Kwon; Ibrahim, Tamer M; Oh, Chang-Hyun.
Affiliation
  • Mersal KI; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Cairo, 12055, Egypt; University of Science & Technology (UST), Daejeon, Yuseong-gu, 34113, Republic of Korea; Center of Biomaterials, Korea Institute of Science & Technology (KIS
  • Abdel-Maksoud MS; Medicinal & Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre NRC (ID: 60014618), Dokki, Giza, 12622, Egypt.
  • Ali EMH; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Cairo, 12055, Egypt; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 575 West Stadium Avenue, West Lafayette, IN, 47907, USA.
  • Ammar UM; School of Applied Sciences, Edinburgh Napier University, Sighthill Campus, 9 Sighthill Court, Edinburgh, EH11 4BN, United Kingdom.
  • Zaraei SO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates.
  • Haque MM; Department of Neural and Pain Sciences, School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA.
  • Das T; Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, 21205, USA.
  • Hassan NF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Cairo, 12055, Egypt.
  • Kim EE; Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, 02792, South Korea.
  • Lee JS; Department of Pharmacology, College of Medicine, Korea University, Seoul, 02841, South Korea.
  • Park H; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, USA.
  • Lee KH; Center for Advanced Biomolecular Recognition, Korea Institute of Science & Technology (KIST School), Seoul, Seongbuk-gu, 02792, Republic of Korea; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea.
  • El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura Unive
  • Kim HK; Department of Nuclear Medicine, Molecular Imaging & Therapeutic Medicine Research Center, Jeonbuk National University Medical School and Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju, 54907, Republic of Korea; Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Researc
  • Ibrahim TM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, P.O. Box 33516, Egypt.
  • Oh CH; University of Science & Technology (UST), Daejeon, Yuseong-gu, 34113, Republic of Korea; Center of Biomaterials, Korea Institute of Science & Technology (KIST School), Seoul, Seongbuk-gu, 02792, Republic of Korea. Electronic address: choh@kist.re.kr.
Eur J Med Chem ; 261: 115779, 2023 Dec 05.
Article in En | MEDLINE | ID: mdl-37776574
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azoles / JNK Mitogen-Activated Protein Kinases Limits: Animals Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Country of publication: Francia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azoles / JNK Mitogen-Activated Protein Kinases Limits: Animals Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Country of publication: Francia