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Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies.
Furie, Nadav; Mandelboim, Michal; Zuckerman, Neta; Belkin, Ana; Seluk, Lior; Shafran, Inbal; Mass, Ronen; Levy, Liran; Chatterji, Sumit; Baltaxe, Erik; Peled, Michael; Shulimzon, Tiberiu; Avigdor, Abraham; Amit, Sharon; Onn, Amir; Marom, Edith M; Rahav, Galia; Segel, Michael J.
Affiliation
  • Furie N; Institute of Pulmonology, Sheba Medical Center, Tel Hashomer, Israel.
  • Mandelboim M; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Zuckerman N; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Belkin A; Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
  • Seluk L; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Shafran I; Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
  • Mass R; Internal Medicine D, Sheba Medical Center, Tel Hashomer, Israel.
  • Levy L; Infectious Diseases Unit, Sheba Medical Center, Tel Hashomer, Israel.
  • Chatterji S; Institute of Pulmonology, Sheba Medical Center, Tel Hashomer, Israel.
  • Baltaxe E; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Peled M; Institute of Pulmonology, Sheba Medical Center, Tel Hashomer, Israel.
  • Shulimzon T; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Avigdor A; Institute of Pulmonology, Sheba Medical Center, Tel Hashomer, Israel.
  • Amit S; Institute of Pulmonology, Sheba Medical Center, Tel Hashomer, Israel.
  • Onn A; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Marom EM; Institute of Pulmonology, Sheba Medical Center, Tel Hashomer, Israel.
  • Rahav G; Institute of Pulmonology, Sheba Medical Center, Tel Hashomer, Israel.
  • Segel MJ; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Open Forum Infect Dis ; 10(10): ofad464, 2023 Oct.
Article in En | MEDLINE | ID: mdl-37808896
ABSTRACT
We report 8 cases of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in patients previously treated with anti-CD20 monoclonal antibodies. Polymerase chain reaction of nasopharyngeal swabs for SARS-CoV-2 was negative in most cases; viral cell cultures confirmed that viable SARS-Co-2 virus was present. Four patients were treated with anti-SARS-CoV-2 hyperimmune globulins with rapid resolution of disease.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Open Forum Infect Dis Year: 2023 Document type: Article Affiliation country: Israel

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Open Forum Infect Dis Year: 2023 Document type: Article Affiliation country: Israel