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Cetuximab every 2 weeks versus standard weekly dosing administration schedule.
Bokemeyer, Carsten; Ciardiello, Fortunato; Dubreuil, Olivier; Guigay, Joel; Kasper, Stefan; Pfeiffer, Per; Pinto, Carmine; Yamaguchi, Kensei; Yoshino, Takayuki; Zielinski, Christoph; Esser, Regina; Tabernero, Josep.
Affiliation
  • Bokemeyer C; The II Medical Clinic, Department of Oncology, Hematology & BMT with section of Pneumology, University Medical Center of Hamburg-Eppendorf, Hamburg, Germany.
  • Ciardiello F; Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
  • Dubreuil O; Medical Oncology Unit, Diaconesses-Croix St Simon Hospital, Paris, France.
  • Guigay J; Groupe d'Oncologie Radiothérapie Tête Et Cou (GORTEC), Tours, France.
  • Kasper S; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.
  • Pfeiffer P; Department of Oncology, Odense University Hospital, Odense, Denmark.
  • Pinto C; Medical Oncology, Comprehensive Cancer Center, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy.
  • Yamaguchi K; Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Yoshino T; Department of Gastroenterology & Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Zielinski C; Central European Cooperative Oncology Group, Vienna, Austria.
  • Esser R; Merck Healthcare KGaA, Darmstadt, Germany.
  • Tabernero J; Medical Oncology Department, Vall d'Hebron Hospital Campus & Institute of Oncology (VHIO), IOB-Quiron, UVic-UCC, Barcelona, Spain.
Future Oncol ; 20(7): 393-407, 2024 Mar.
Article in En | MEDLINE | ID: mdl-37850363
Cetuximab is a drug for patients with colorectal cancer or cancer of the head and neck. It is usually administered once a week. However, studies have shown that cetuximab given once every 2 weeks instead has similar clinical benefits and side effects. Based on this evidence, the every 2 weeks dosing schedule has been approved for use in USA and Japan. The every 2 weeks dosing schedule is a convenient alternative to the weekly schedule. It may result in fewer hospital visits, improved patient quality of life, reduced healthcare costs and more flexibility for medical staff. This review summarizes the current evidence and benefits for the every 2 weeks dosing schedule.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell Limits: Humans Language: En Journal: Future Oncol Year: 2024 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell Limits: Humans Language: En Journal: Future Oncol Year: 2024 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido