Role of rafts in neurological disorders.
Neurologia (Engl Ed)
; 38(9): 671-680, 2023.
Article
in En
| MEDLINE
| ID: mdl-37858892
ABSTRACT
INTRODUCTION:
Rafts are protein-lipid structural nanodomains involved in efficient signal transduction and the modulation of physiological processes of the cell plasma membrane. Raft disruption in the nervous system has been associated with a wide range of disorders. DEVELOPMENT We review the concept of rafts, the nervous system processes in which they are involved, and their role in diseases such as Parkinson's disease, Alzheimer disease, and Huntington disease.CONCLUSIONS:
Based on the available evidence, preservation and/or reconstitution of rafts is a promising treatment strategy for a wide range of neurological disorders.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Caveolae
/
Alzheimer Disease
Limits:
Humans
Language:
En
Journal:
Neurologia (Engl Ed)
Year:
2023
Document type:
Article