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Predicting Colloidal Stability of High-Concentration Monoclonal Antibody Formulations in Common Pharmaceutical Buffers Using Improved Polyethylene Glycol Induced Protein Precipitation Assay.
Meza, Noemi P; Hardy, Colin A; Morin, Kylie H; Huang, Chengbin; Raghava, Smita; Song, Jing; Zhang, Jingtao; Wang, Ying.
Affiliation
  • Meza NP; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
  • Hardy CA; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
  • Morin KH; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
  • Huang C; Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Raghava S; Sterile and Specialty Products, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Song J; Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Zhang J; Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Wang Y; Department of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28403, United States.
Mol Pharm ; 20(11): 5842-5855, 2023 11 06.
Article in En | MEDLINE | ID: mdl-37867303
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Antibodies, Monoclonal Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Antibodies, Monoclonal Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2023 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos