Eosinophils in Traditionally Noneosinophil-Rich Dermatoses.
Am J Dermatopathol
; 45(12): 820-821, 2023 Dec 01.
Article
in En
| MEDLINE
| ID: mdl-37883982
ABSTRACT
ABSTRACT The presence or absence of tissue eosinophilia has previously aided in the diagnosis of inflammatory skin conditions. However, recent studies have elucidated the presence of eosinophils in traditionally eosinophil-poor inflammatory skin diseases, such as dermatomyositis (DM), psoriasis, and lichen sclerosus (LS). This systematic review of the literature explores previous studies of tissue eosinophilia in skin biopsies of dermatoses that are believed to be classically poor in eosinophil. We identified 26 studies, the majority of which were retrospective reviews. The percent of specimens with increased eosinophils in psoriasis ranged from 18%-73%, pityriasis rubra pilaris (PRP) 22%-63%, LS 29%-53%, DM 15%-44%, morphea 8%-45%, hypertrophic lichen planus (LP) 0%-21%, and oral LP 0%-4%. These reports of tissue eosinophilia in reputed eosinophil-poor dermatologic conditions present a diagnostic pitfall and suggest that tissue eosinophilia itself should not be used to rule out a diagnosis of one of these conditions.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pityriasis Rubra Pilaris
/
Psoriasis
/
Lichen Sclerosus et Atrophicus
/
Eosinophilia
Type of study:
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Am J Dermatopathol
Year:
2023
Document type:
Article
Affiliation country:
Canadá