Use of mexiletine in therapy-refractory recurrent ventricular tachycardia storm.
Herzschrittmacherther Elektrophysiol
; 34(4): 326-329, 2023 Dec.
Article
in En
| MEDLINE
| ID: mdl-37917362
ABSTRACT
Electrical storm due to recurrent ventricular tachycardias (VTs) is a life-threatening arrhythmic emergency. The authors present a case report of a 69-year-old male patient with VT storm of non-ischemic etiology. Despite optimal medical treatment escalated by amiodarone antiarrhythmic drug therapy, the patient experienced multiple implantable cardioverter defibrillator (ICD) shocks. An electrophysiological study revealed an epicardial substrate; however, considering the patient's extreme obesity and active anticoagulant effect, catheter ablation was deemed to be unfeasible. Subsequently, mexiletine was added to the patient's drug regimen, resulting in successful control of arrhythmias during the following 6 months. Although the most recent European guidelines for the management of patients with ventricular arrhythmias mention mexiletine only for the treatment of LQT3 patients, its use for treatment-refractory VT storm seems to also be an important indication area.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tachycardia, Ventricular
/
Defibrillators, Implantable
/
Catheter Ablation
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
Herzschrittmacherther Elektrophysiol
Journal subject:
CARDIOLOGIA
/
FISIOLOGIA
Year:
2023
Document type:
Article
Affiliation country:
Hungria