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Drug repurposing for the treatment of COVID-19: Targeting nafamostat to the lungs by a liposomal delivery system.
Reus, Philipp; Guthmann, Hadar; Uhlig, Nadja; Agbaria, Majd; Issmail, Leila; Eberlein, Valentina; Nordling-David, Mirjam M; Jbara-Agbaria, Doaa; Ciesek, Sandra; Bojkova, Denisa; Cinatl, Jindrich; Burger-Kentischer, Anke; Rupp, Steffen; Zaliani, Andrea; Grunwald, Thomas; Gribbon, Philip; Kannt, Aimo; Golomb, Gershon.
Affiliation
  • Reus P; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Schnackenburgallee 114, 22525 Hamburg, Germany; Goethe University Frankfurt, University Hospital, Institute for Medical Virology, Paul-Ehrlich-Straße 40, 60596 Frankfurt am Main, Germany.
  • Guthmann H; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel; The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
  • Uhlig N; Fraunhofer Institute for Cell Therapy und Immunology IZI, Perlickstrasse 1, 04103 Leipzig, Germany.
  • Agbaria M; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
  • Issmail L; Fraunhofer Institute for Cell Therapy und Immunology IZI, Perlickstrasse 1, 04103 Leipzig, Germany.
  • Eberlein V; Fraunhofer Institute for Cell Therapy und Immunology IZI, Perlickstrasse 1, 04103 Leipzig, Germany.
  • Nordling-David MM; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
  • Jbara-Agbaria D; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
  • Ciesek S; Goethe University Frankfurt, University Hospital, Institute for Medical Virology, Paul-Ehrlich-Straße 40, 60596 Frankfurt am Main, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany.
  • Bojkova D; Goethe University Frankfurt, University Hospital, Institute for Medical Virology, Paul-Ehrlich-Straße 40, 60596 Frankfurt am Main, Germany.
  • Cinatl J; Goethe University Frankfurt, University Hospital, Institute for Medical Virology, Paul-Ehrlich-Straße 40, 60596 Frankfurt am Main, Germany.
  • Burger-Kentischer A; Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstraße 12, 70569 Stuttgart, Germany.
  • Rupp S; Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstraße 12, 70569 Stuttgart, Germany.
  • Zaliani A; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Schnackenburgallee 114, 22525 Hamburg, Germany.
  • Grunwald T; Fraunhofer Institute for Cell Therapy und Immunology IZI, Perlickstrasse 1, 04103 Leipzig, Germany.
  • Gribbon P; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, Schnackenburgallee 114, 22525 Hamburg, Germany.
  • Kannt A; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany; Fraunhofer Innovation Center TheraNova, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany; Institute for Clinical Pharmacology, Goethe University Frankfurt, Theodor-Stern
  • Golomb G; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel; The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
J Control Release ; 364: 654-671, 2023 Dec.
Article in En | MEDLINE | ID: mdl-37939853
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Limits: Animals / Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2023 Document type: Article Affiliation country: Alemania
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Limits: Animals / Humans Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2023 Document type: Article Affiliation country: Alemania