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Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aß oligomer profiles unaltered by ablation of cellular prion protein.
Purro, Silvia A; Farmer, Michael; Noble, Elizabeth; Sarell, Claire J; Powell, Megan; Yip, Daniel; Giggins, Lauren; Zakka, Leila; Thomas, David X; Farrow, Mark; Nicoll, Andrew J; Walsh, Dominic; Collinge, John.
Affiliation
  • Purro SA; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Farmer M; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Noble E; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Sarell CJ; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Powell M; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Yip D; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Giggins L; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Zakka L; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Thomas DX; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Farrow M; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Nicoll AJ; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Walsh D; MRC Prion Unit at UCL, Institute of Prion diseases, University College London, London, United Kingdom.
  • Collinge J; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
PLoS One ; 18(11): e0294465, 2023.
Article in En | MEDLINE | ID: mdl-37976283

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prions / PrPC Proteins / Alzheimer Disease Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prions / PrPC Proteins / Alzheimer Disease Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2023 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos