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Phase 1b study of enzalutamide plus CC-115, a dual mTORC1/2 and DNA-PK inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC).
Zhao, Jimmy L; Antonarakis, Emmanuel S; Cheng, Heather H; George, Daniel J; Aggarwal, Rahul; Riedel, Elyn; Sumiyoshi, Takayuki; Schonhoft, Joseph D; Anderson, Amanda; Mao, Ninghui; Haywood, Samuel; Decker, Brooke; Curley, Tracy; Abida, Wassim; Feng, Felix Y; Knudsen, Karen; Carver, Brett; Lacouture, Mario E; Wyatt, Alexander W; Rathkopf, Dana.
Affiliation
  • Zhao JL; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Antonarakis ES; University of Minnesota Masonic Cancer Center, Minneapolis, MN, 55455, USA.
  • Cheng HH; The Sidney Kimmel Cancer Comprehensive Cancer Center at Johns Hopkins, 401 N. Broadway, Baltimore, MD, 21231, USA.
  • George DJ; R&D in Oncology, AstraZeneca, New York, NY, 10016, USA.
  • Aggarwal R; University of Washington and Fred Hutch Cancer Research Center, 1144 Eastlake Avenue, Seattle, WA, 98109, USA.
  • Riedel E; Duke Cancer Institute, 20 Duke Medicine Circle, Durham, NC, 27710, USA.
  • Sumiyoshi T; University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, 1825 4th Street, San Francisco, CA, 94158, USA.
  • Schonhoft JD; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Anderson A; Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.
  • Mao N; Epic Sciences, 9381 Judicial Drive Suite 200, San Diego, CA, 92121, USA.
  • Haywood S; Epic Sciences, 9381 Judicial Drive Suite 200, San Diego, CA, 92121, USA.
  • Decker B; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Curley T; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Abida W; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Feng FY; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Knudsen K; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Carver B; University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, 1825 4th Street, San Francisco, CA, 94158, USA.
  • Lacouture ME; Sidney Kimmel Cancer Center, Thomas Jefferson University, 914 Chestnut Street, Philadelphia, PA, 19107, USA.
  • Wyatt AW; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
  • Rathkopf D; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
Br J Cancer ; 130(1): 53-62, 2024 01.
Article in En | MEDLINE | ID: mdl-37980367
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylthiohydantoin / Pyrazines / Triazoles / Benzamides / Prostatic Neoplasms, Castration-Resistant Limits: Humans / Male Language: En Journal: Br J Cancer Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylthiohydantoin / Pyrazines / Triazoles / Benzamides / Prostatic Neoplasms, Castration-Resistant Limits: Humans / Male Language: En Journal: Br J Cancer Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido