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LDP-GAN : Generative adversarial networks with local differential privacy for patient medical records synthesis.
Gwon, Hansle; Ahn, Imjin; Kim, Yunha; Kang, Hee Jun; Seo, Hyeram; Choi, Heejung; Cho, Ha Na; Kim, Minkyoung; Han, JiYe; Kee, Gaeun; Park, Seohyun; Lee, Kye Hwa; Jun, Tae Joon; Kim, Young-Hak.
Affiliation
  • Gwon H; Department of Information Medicine, Asan Medical Center, 8, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Ahn I; Department of Information Medicine, Asan Medical Center, 8, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Kim Y; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Kang HJ; Division of Cardiology, Asan Medical Center, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Seo H; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Choi H; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Cho HN; Department of Information Medicine, Asan Medical Center, 8, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Kim M; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Han J; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Kee G; Department of Information Medicine, Asan Medical Center, 8, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Park S; Department of Information Medicine, Asan Medical Center, 8, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Lee KH; Department of Information Medicine, Asan Medical Center, 8, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
  • Jun TJ; Big Data Research Center, Asan Institute for Life Sciences, Asan Medical Center, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea. Electronic address: taejoon@amc.seoul.kr.
  • Kim YH; Division of Cardiology, Department of Information Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Comput Biol Med ; 168: 107738, 2024 01.
Article in En | MEDLINE | ID: mdl-37995536
ABSTRACT
Electronic medical records(EMR) have considerable potential to advance healthcare technologies, including medical AI. Nevertheless, due to the privacy issues associated with the sharing of patient's personal information, it is difficult to sufficiently utilize them. Generative models based on deep learning can solve this problem by creating synthetic data similar to real patient data. However, the data used for training these deep learning models run into the risk of getting leaked because of malicious attacks. This means that traditional deep learning-based generative models cannot completely solve the privacy issues. Therefore, we suggested a method to prevent the leakage of training data by protecting the model from malicious attacks using local differential privacy(LDP). Our method was evaluated in terms of utility and privacy. Experimental results demonstrated that the proposed method can generate medical data with reasonable performance while protecting training data from malicious attacks.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Privacy / Electronic Health Records Limits: Humans Language: En Journal: Comput Biol Med Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Privacy / Electronic Health Records Limits: Humans Language: En Journal: Comput Biol Med Year: 2024 Document type: Article