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ME3183, a novel phosphodiesterase-4 inhibitor, exhibits potent anti-inflammatory effects and is well tolerated in a non-clinical study.
Kubota-Ishida, Natsuki; Kaji, Chizuko; Matsumoto, Shogo; Wakabayashi, Tsubasa; Matsuhira, Takashi; Okura, Iori; Cho, Naoki; Isshiki, Satoshi; Kumura, Ko; Tabata, Yuji.
Affiliation
  • Kubota-Ishida N; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan. Electronic address: natsuki.ishida@meiji.com.
  • Kaji C; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Matsumoto S; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Wakabayashi T; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Matsuhira T; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Okura I; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Cho N; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Isshiki S; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Kumura K; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
  • Tabata Y; R&D Division, Meiji Seika Pharma Co., Ltd., 2-4-16, Kyobashi, Chuo-ku, Tokyo, 104-8002, Japan.
Eur J Pharmacol ; 962: 176202, 2024 Jan 05.
Article in En | MEDLINE | ID: mdl-37996010
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Dermatitis, Atopic / Phosphodiesterase 4 Inhibitors Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 2024 Document type: Article Country of publication: Países Bajos
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Dermatitis, Atopic / Phosphodiesterase 4 Inhibitors Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 2024 Document type: Article Country of publication: Países Bajos