Thin and Plain Supplementary Motor Area in Chronic Ankle Instability: A Volume and Surface-based Morphometric Study.
J Athl Train
; 2023 Nov 28.
Article
in En
| MEDLINE
| ID: mdl-38014788
ABSTRACT
CONTEXT The supplementary motor area (SMA) is involved in the functional deficits of chronic ankle instability (CAI), but the structural basis of its abnormalities remains unclear. OBJECTIVE:
To determine the differences in volume and surface-based morphological features of SMA between patients with CAI and healthy controls, and their relationship with the clinical features of CAI.DESIGN:
Cross-sectional study.SETTING:
Sports medicine laboratory. PATIENTS OR OTHERPARTICIPANTS:
A total of 32 CAI patients (10 females; age 32.46 ± 7.51 years) and 31 healthy controls (12 females; age 29.70 ± 8.07 years) participated in this study. MAIN OUTCOME MEASURE(S) Participants perform T1 structural magnetic resonance imaging and calculate volume and surface-based morphological features of SMA subregions. These included anterior and posterior subdivisions of Brodmann's area 6 m (6 ma/6 mp), and supplementary and cingulate eye fields. Between-group comparisons and correlation analysis with clinical features of CAI were performed.RESULTS:
Moderately thinner 6 mp (Cohen's d = -0.61) and moderately plainer 6 ma (Cohen's d = -0.70) were observed in patients compared with controls. Before and after regressing out the covariates, the thinner 6 mp was correlated with the lower foot and ankle ability measure scores of daily activities (r-before=0.400, r-after = 0.449).CONCLUSIONS:
Patients with CAI had a thinner posterior subdivision (motor-output site) and a plainer anterior subdivision (motor-planning site) of SMA than that of controls. The thin motor-output site of the SMA is associated with ankle dysfunction in patients. These morphologic evidence of maladaptive neuroplasticity in SMA might promote more targeted rehabilitation of CAI.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Athl Train
Year:
2023
Document type:
Article
Affiliation country:
China