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Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data.
O'Donovan, Shauna D; Cavill, Rachel; Wimmenauer, Florian; Lukas, Alexander; Stumm, Tobias; Smirnov, Evgueni; Lenz, Michael; Ertaylan, Gokhan; Jennen, Danyel G J; van Riel, Natal A W; Driessens, Kurt; Peeters, Ralf L M; de Kok, Theo M C M.
Affiliation
  • O'Donovan SD; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, Maastricht, The Netherlands.
  • Cavill R; Dept. of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
  • Wimmenauer F; Eindhoven Artificial Intelligence Systems Institute (EAISI), Eindhoven University of Technology, Eindhoven, The Netherlands.
  • Lukas A; Dept. of Advanced Computing Sciences, Maastricht University, Maastricht, The Netherlands.
  • Stumm T; Dept. of Advanced Computing Sciences, Maastricht University, Maastricht, The Netherlands.
  • Smirnov E; Dept. of Advanced Computing Sciences, Maastricht University, Maastricht, The Netherlands.
  • Lenz M; Dept. of Advanced Computing Sciences, Maastricht University, Maastricht, The Netherlands.
  • Ertaylan G; Dept. of Advanced Computing Sciences, Maastricht University, Maastricht, The Netherlands.
  • Jennen DGJ; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, Maastricht, The Netherlands.
  • van Riel NAW; Institute of Organismic and Molecular Evolution, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Driessens K; Preventive Cardiology and Preventative Medicine - Center for Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
  • Peeters RLM; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, Maastricht, The Netherlands.
  • de Kok TMCM; Sustainable Health, Flemish Institute for Technological Research (VITO), Mol, Belgium.
PLoS One ; 18(11): e0292030, 2023.
Article in En | MEDLINE | ID: mdl-38032940
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neural Networks, Computer / Liver Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2023 Document type: Article Affiliation country: Países Bajos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neural Networks, Computer / Liver Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2023 Document type: Article Affiliation country: Países Bajos