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Influence of Gut Microbiota and its Metabolites on Progression of Metabolic Associated Fatty Liver Disease.
Wang, Yuan-Yuan; Lin, Hai-Lian; Wang, Ke-Lang; Que, Gen-Xiang; Cao, Ting; Zhu, La-Mei; Yang, Xia; Yang, Xue-Feng.
Affiliation
  • Wang YY; Hunan Provincial Clinical Research Center for Metabolic Associated Fatty Liver Disease, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
  • Lin HL; Department of Gastroenterology, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
  • Wang KL; Hunan Provincial Clinical Research Center for Metabolic Associated Fatty Liver Disease, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
  • Que GX; Department of Gastroenterology, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
  • Cao T; Hunan Provincial Clinical Research Center for Metabolic Associated Fatty Liver Disease, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
  • Zhu LM; Department of Gastroenterology, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
  • Yang X; Hunan Provincial Clinical Research Center for Metabolic Associated Fatty Liver Disease, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
  • Yang XF; Department of Gastroenterology, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China, Hengyang, Hunan 421002, China.
Chin Med Sci J ; 38(4): 286-296, 2023 Dec.
Article in En | MEDLINE | ID: mdl-38097345
ABSTRACT
Metabolic associated fatty liver disease (MAFLD) has become a prevalent chronic liver disease worldwide because of lifestyle and dietary changes. Gut microbiota and its metabolites have been shown to play a critical role in the pathogenesis of MAFLD. Understanding of the function of gut microbiota and its metabolites in MAFLD may help to elucidate pathological mechanisms, identify diagnostic markers, and develop drugs or probiotics for the treatment of MAFLD. Here we review the pathogenesis of MAFLD by gut microbiota and its metabolites and discuss the feasibility of treating MAFLD from the perspective of gut microbes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fatty Liver / Gastrointestinal Microbiome Limits: Humans Language: En Journal: Chin Med Sci J Journal subject: TERAPIAS COMPLEMENTARES Year: 2023 Document type: Article Affiliation country: China Country of publication: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fatty Liver / Gastrointestinal Microbiome Limits: Humans Language: En Journal: Chin Med Sci J Journal subject: TERAPIAS COMPLEMENTARES Year: 2023 Document type: Article Affiliation country: China Country of publication: China