Concurrent gliomas in patients with multiple sclerosis.
Commun Med (Lond)
; 3(1): 186, 2023 Dec 18.
Article
in En
| MEDLINE
| ID: mdl-38110626
Brain tumors such as gliomas can evade attacks by the immune system. In contrast, some diseases of the central nervous system such as multiple sclerosis (MS) are caused by an overactive immune system. Our study looks at a cohort of rare patients with both malignant glioma and concurrent MS and examines how each disease and their treatments affect each other. Our data suggest that even in patients with known MS, if medical imaging findings are unusual, a concurrent brain tumor should be excluded at an early stage. Radiotherapy, as is the standard of care for malignant brain tumors, may worsen the inflammatory disease activity in MS patients, which may be associated with certain genetic risk factors. Our findings may help to inform treatment of patients with brain tumors and MS.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Commun Med (Lond)
Year:
2023
Document type:
Article
Affiliation country:
Alemania
Country of publication:
Reino Unido