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Precision microbial intervention improves social behavior but not autism severity: A pilot double-blind randomized placebo-controlled trial.
Mazzone, Luigi; Dooling, Sean W; Volpe, Elisabetta; Uljarevic, Mirko; Waters, Jillian L; Sabatini, Andrea; Arturi, Lucrezia; Abate, Roberta; Riccioni, Assia; Siracusano, Martina; Pereira, Marcela; Engstrand, Lars; Cristofori, Fernanda; Adduce, Domenico; Francavilla, Ruggiero; Costa-Mattioli, Mauro; Hardan, Antonio Y.
Affiliation
  • Mazzone L; Child Neurology and Psychiatry Unit, Department of Neurosciences, Policlinico Tor Vergata Foundation Hospital, Viale Oxford 81, 00133 Rome, Italy; Systems Medicine Department, University of Rome Tor Vergata, Montpellier Street 1, 00133 Rome, Italy. Electronic address: luigi.mazzone@ptvonline.it.
  • Dooling SW; Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA; Memory and Brain Research Center, Baylor College of Medicine, Houston, TX, USA; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Altos Labs, Inc, Bay Area Institute of Science,
  • Volpe E; Molecular Neuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy.
  • Uljarevic M; Melbourne School of Psychological Sciences, University of Melbourne, Tin Alley, Carlton, Melbourne, VIC 3010, Australia.
  • Waters JL; Altos Labs, Inc, Bay Area Institute of Science, Redwood City, CA 94065, USA.
  • Sabatini A; Molecular Neuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy.
  • Arturi L; Child Neurology and Psychiatry Unit, Department of Neurosciences, Policlinico Tor Vergata Foundation Hospital, Viale Oxford 81, 00133 Rome, Italy; Systems Medicine Department, University of Rome Tor Vergata, Montpellier Street 1, 00133 Rome, Italy.
  • Abate R; Child Neurology and Psychiatry Unit, Department of Neurosciences, Policlinico Tor Vergata Foundation Hospital, Viale Oxford 81, 00133 Rome, Italy.
  • Riccioni A; Child Neurology and Psychiatry Unit, Department of Neurosciences, Policlinico Tor Vergata Foundation Hospital, Viale Oxford 81, 00133 Rome, Italy; Systems Medicine Department, University of Rome Tor Vergata, Montpellier Street 1, 00133 Rome, Italy.
  • Siracusano M; Child Neurology and Psychiatry Unit, Department of Neurosciences, Policlinico Tor Vergata Foundation Hospital, Viale Oxford 81, 00133 Rome, Italy; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Montpellier Street 1, 00133 Rome, Italy.
  • Pereira M; Centre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
  • Engstrand L; Centre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
  • Cristofori F; Pediatric Gastroenterology and Hepatology Unit, Department of Interdisciplinary Medicine, Children's Hospital-Giovanni XXIII, University of Bari Aldo Moro, 70121 Bari, Italy.
  • Adduce D; Pediatric Gastroenterology and Hepatology Unit, Department of Interdisciplinary Medicine, Children's Hospital-Giovanni XXIII, University of Bari Aldo Moro, 70121 Bari, Italy.
  • Francavilla R; Pediatric Gastroenterology and Hepatology Unit, Department of Interdisciplinary Medicine, Children's Hospital-Giovanni XXIII, University of Bari Aldo Moro, 70121 Bari, Italy.
  • Costa-Mattioli M; Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA; Memory and Brain Research Center, Baylor College of Medicine, Houston, TX, USA; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Altos Labs, Inc, Bay Area Institute of Science,
  • Hardan AY; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA. Electronic address: hardanay@stanford.edu.
Cell Host Microbe ; 32(1): 106-116.e6, 2024 Jan 10.
Article in En | MEDLINE | ID: mdl-38113884
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder Limits: Animals / Child / Humans Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2024 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder Limits: Animals / Child / Humans Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2024 Document type: Article Country of publication: Estados Unidos