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L-cysteine ethylester reverses the adverse effects of morphine on breathing and arterial blood-gas chemistry while minimally affecting antinociception in unanesthetized rats.
Baby, Santhosh M; May, Walter J; Young, Alex P; Wilson, Christopher G; Getsy, Paulina M; Coffee, Gregory A; Lewis, Tristan H J; Hsieh, Yee-Hee; Bates, James N; Lewis, Stephen J.
Affiliation
  • Baby SM; Department of Drug Discovery, Galleon Pharmaceuticals, Inc., Horsham, PA, USA.
  • May WJ; Pediatric Respiratory Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.
  • Young AP; Pediatric Respiratory Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.
  • Wilson CG; Basic Sciences, Division of Physiology, School of Medicine, Loma Linda University, USA.
  • Getsy PM; Department of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
  • Coffee GA; Department of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
  • Lewis THJ; Lerner Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Hsieh YH; Division of Pulmonary, Critical Care and Sleep Medicine, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA.
  • Bates JN; Department of Anesthesia, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Lewis SJ; Department of Pediatrics, Case Western Reserve University, Cleveland, OH, USA; Department of Pharmacology, Case Western Reserve University, Cleveland, OH, USA. Electronic address: sjl78@case.edu.
Biomed Pharmacother ; 171: 116081, 2024 Feb.
Article in En | MEDLINE | ID: mdl-38219385

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug-Related Side Effects and Adverse Reactions / Morphine Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Francia

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug-Related Side Effects and Adverse Reactions / Morphine Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Francia