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Nomogram for predicting prolonged postoperative ileus in colorectal cancer based on age and inflammatory markers.
Fan, Zong-Qi; Chen, Yang; Fu, Xin-Ao; Yin, Hao-Ting; Li, Ju-Shang; Wang, Wei-Si; Yuan, Jie-Qing; Guo, Shi-Gang.
Affiliation
  • Fan ZQ; Department of Gastrointestinal Surgery, Chaoyang Central Hospital Postgraduate Training Base of Jinzhou Medical University, Liaoning Province, 122000, PR China.
  • Chen Y; Department of Gastrointestinal Surgery, Chaoyang Central Hospital, Liaoning Province, 122000, PR China.
  • Fu XA; Department of Gastrointestinal Surgery, Chaoyang Central Hospital, Liaoning Province, 122000, PR China.
  • Yin HT; China Medical University, Liaoning Province, 110000, PR China.
  • Li JS; Department of Gastrointestinal Surgery, Chaoyang Central Hospital Postgraduate Training Base of Jinzhou Medical University, Liaoning Province, 122000, PR China.
  • Wang WS; Department of Gastrointestinal Surgery, Chaoyang Central Hospital, Liaoning Province, 122000, PR China.
  • Yuan JQ; China Medical University, Liaoning Province, 110000, PR China.
  • Guo SG; Department of Gastrointestinal Surgery, Chaoyang Central Hospital, Liaoning Province, 122000, PR China.
Biomark Med ; 17(22): 921-933, 2023 11.
Article in En | MEDLINE | ID: mdl-38235563
ABSTRACT

Aim:

To explore the relationship between inflammatory markers and prolonged postoperative ileus (PPOI), and to establish a nomogram for predicting PPOI. Patients &

methods:

The data of 229 patients were analyzed retrospectively. Univariate and multivariate logistic regression analysis were used to analyze the risk factors affecting the occurrence of PPOI. The predictive model of PPOI was established and verified internally.

Results:

Postoperative PPOI occurred in 87 (38.0%) of all 229 patients. Our study showed that age, preoperative neutrophil-lymphocyte ratio and changes in neutrophil-lymphocyte ratio were independent risk factors for PPOI.

Conclusion:

The nomograms established based on these independent risk factors have good predictive efficacy and may be able to guide clinicians to individualize the diagnosis and treatment.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Ileus Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Biomark Med Journal subject: BIOQUIMICA / MEDICINA Year: 2023 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Ileus Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Biomark Med Journal subject: BIOQUIMICA / MEDICINA Year: 2023 Document type: Article