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Abdominal rhabdoid tumor presenting with symptomatic spinal epidural compression in a newborn. A case report.
Montalto, Shana; Di Filippo, Michela; Capra, Valeria; Manzitti, Carla; Sementa, Angela Rita; De Marco, Patrizia; Ognibene, Marzia; Sertorio, Fiammetta; Sorrentino, Stefania.
Affiliation
  • Montalto S; Pediatric Infectious Diseases Unit, IRCCS IstitutoGianninaGaslini, Genoa, Italy.
  • Di Filippo M; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
  • Capra V; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
  • Manzitti C; Genomics and Clinical Genetics Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
  • Sementa AR; Oncology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
  • De Marco P; Department of Pathology, IRCCS IstitutoGianninaGaslini, Genoa, Italy.
  • Ognibene M; Medical Genetics Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
  • Sertorio F; Medical Genetics Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
  • Sorrentino S; Radiology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Front Pediatr ; 11: 1337760, 2023.
Article in En | MEDLINE | ID: mdl-38283400
ABSTRACT
The occurrence of an abdominal tumor invading the spinal canal and causing symptoms of epidural compression is rare in an infant, and exceptional at birth. Peripheral neuroblastic tumors are by far the most common cause. Emergency chemotherapy is commonly curative, though permanent sequelae are possible. Although other malignancies may be involved, no case of rhabdoid tumors at birth has been reported. We describe the case of a neonate who presented symptoms of spinal epidural compression at birth secondary to a rhabdoid tumor. As expected with this highly malignant tumor, the patient experienced a rapidly progressive clinical course and died within three months of diagnosis.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Front Pediatr Year: 2023 Document type: Article Affiliation country: Italia

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: Front Pediatr Year: 2023 Document type: Article Affiliation country: Italia