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SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming.
Xu, Xi; Yu, Yanhui; Zhang, Wenwen; Ma, Weiwei; He, Chong; Qiu, Guo; Wang, Xinyi; Liu, Qiong; Zhao, Minyi; Xie, Jiayi; Tao, Fang; Perry, John M; Liu, Qifa; Rao, Shuan; Kang, Xunlei; Zhao, Meng; Jiang, Linjia.
Affiliation
  • Xu X; RNA Biomedical Institute, Sun Yat-sen Memorial Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Yu Y; Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Zhang W; Advanced Medical Technology Center, The First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University Guangzhou, Guangdong, China.
  • Ma W; Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • He C; Department of Hematology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China.
  • Qiu G; Advanced Medical Technology Center, The First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University Guangzhou, Guangdong, China.
  • Wang X; Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Liu Q; Advanced Medical Technology Center, The First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University Guangzhou, Guangdong, China.
  • Zhao M; Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Xie J; RNA Biomedical Institute, Sun Yat-sen Memorial Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Tao F; Advanced Medical Technology Center, The First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University Guangzhou, Guangdong, China.
  • Perry JM; Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Liu Q; Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Rao S; RNA Biomedical Institute, Sun Yat-sen Memorial Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Kang X; Advanced Medical Technology Center, The First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University Guangzhou, Guangdong, China.
  • Zhao M; Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Jiang L; Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Nat Cell Biol ; 26(3): 464-477, 2024 Mar.
Article in En | MEDLINE | ID: mdl-38321204
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Metabolic Reprogramming Limits: Humans Language: En Journal: Nat Cell Biol Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Metabolic Reprogramming Limits: Humans Language: En Journal: Nat Cell Biol Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido