Brain natriuretic peptide in acute heart failure and its association with glomerular filtration rate: A systematic review and meta-analysis.
Medicine (Baltimore)
; 103(8): e36933, 2024 Feb 23.
Article
in En
| MEDLINE
| ID: mdl-38394539
ABSTRACT
BACKGROUND:
Acute heart failure (AHF) is one of the most common cardiovascular diseases. Early diagnosis and prognosis are essential, as they can eventually lead to a fatal condition. Recently, brain natriuretic peptide (BNP) has been recognized as one of the most popular biomarkers for AHF. Changes in glomerular filtration rate (GFR) are often observed in AHF.METHODS:
We searched PubMed, Google Scholar, and ScienceDirect between March and June 2023. Original case control studies written in English that assessed levels oh BNP in AHF were included. Systematic reviews, letters to editor, correspondence, comprehensive reviews, and duplicated studies were excluded. Funnel plots were constructed to assess publication bias.RESULTS:
A total of 9 studies were selected and we obtained the mean difference (MD) of BNP level to be 2.57 (95% CI 1.35, 3.78), and GFR to be -15.52, (95% CI -23.35, -7.70) in AHF patients. Sensitivity analyses supported the robustness of the outcome.CONCLUSION:
Results indicated that BNP was a promising prognostic biomarker of AHF, whereas GFR was found to be negatively correlated with AHF.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Natriuretic Peptide, Brain
/
Heart Failure
Limits:
Humans
Language:
En
Journal:
Medicine (Baltimore)
Year:
2024
Document type:
Article
Affiliation country:
Pakistán
Country of publication:
Estados Unidos