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Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients.
Standing, Joseph F; Buggiotti, Laura; Guerra-Assuncao, Jose Afonso; Woodall, Maximillian; Ellis, Samuel; Agyeman, Akosua A; Miller, Charles; Okechukwu, Mercy; Kirkpatrick, Emily; Jacobs, Amy I; Williams, Charlotte A; Roy, Sunando; Martin-Bernal, Luz M; Williams, Rachel; Smith, Claire M; Sanderson, Theo; Ashford, Fiona B; Emmanuel, Beena; Afzal, Zaheer M; Shields, Adrian; Richter, Alex G; Dorward, Jienchi; Gbinigie, Oghenekome; Van Hecke, Oliver; Lown, Mark; Francis, Nick; Jani, Bhautesh; Richards, Duncan B; Rahman, Najib M; Yu, Ly-Mee; Thomas, Nicholas P B; Hart, Nigel D; Evans, Philip; Andersson, Monique; Hayward, Gail; Hood, Kerenza; Nguyen-Van-Tam, Jonathan S; Little, Paul; Hobbs, F D Richard; Khoo, Saye; Butler, Christopher; Lowe, David M; Breuer, Judith.
Affiliation
  • Standing JF; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK. j.standing@ucl.ac.uk.
  • Buggiotti L; Great Ormond Street Hospital for Children NHS Trust, London, UK. j.standing@ucl.ac.uk.
  • Guerra-Assuncao JA; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Woodall M; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Ellis S; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Agyeman AA; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Miller C; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Okechukwu M; Great Ormond Street Hospital for Children NHS Trust, London, UK.
  • Kirkpatrick E; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Jacobs AI; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Williams CA; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Roy S; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Martin-Bernal LM; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Williams R; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Smith CM; Genetics and Genomic Medicine Department, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Sanderson T; Infection, Immunity and Inflammation, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Ashford FB; Francis Crick Institute, London, UK.
  • Emmanuel B; Clinical Immunology Service, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
  • Afzal ZM; Clinical Immunology Service, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
  • Shields A; Clinical Immunology Service, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
  • Richter AG; Clinical Immunology Service, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
  • Dorward J; Clinical Immunology Service, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
  • Gbinigie O; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Van Hecke O; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
  • Lown M; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Francis N; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Jani B; Primary Care Research Centre, University of Southampton, Southampton, UK.
  • Richards DB; Primary Care Research Centre, University of Southampton, Southampton, UK.
  • Rahman NM; School of Health and Wellbeing, University of Glasgow, Glasgow, UK.
  • Yu LM; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Thomas NPB; Respiratory Trials Unit and Oxford NIHR Biomedical Research Centre, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Hart ND; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Evans P; Windrush Medical Practice, Witney, UK.
  • Andersson M; School of Medicine, Dentistry and Biomedical Sciences. Queen's University Belfast, Belfast, UK.
  • Hayward G; APEx (Exeter Collaboration for Academic Primary Care), University of Exeter Medical School, Exeter, UK.
  • Hood K; National Institute of Health and Care Research, Clinical Research Network, University of Leeds, Leeds, UK.
  • Nguyen-Van-Tam JS; Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Little P; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Hobbs FDR; Centre for Trials Research, Cardiff University, Wales, UK.
  • Khoo S; Lifespan and Population Health, University of Nottingham School of Medicine, Nottingham, UK.
  • Butler C; Primary Care Research Centre, University of Southampton, Southampton, UK.
  • Lowe DM; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
  • Breuer J; Department of Pharmacology, University of Liverpool and Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.
Nat Commun ; 15(1): 1652, 2024 Feb 23.
Article in En | MEDLINE | ID: mdl-38396069
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytidine / SARS-CoV-2 / COVID-19 / Hydroxylamines Limits: Adult / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2024 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytidine / SARS-CoV-2 / COVID-19 / Hydroxylamines Limits: Adult / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2024 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido