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Cross-species real time detection of trends in pupil size fluctuation.
Kronemer, Sharif I; Gobo, Victoria E; Walsh, Catherine R; Teves, Joshua B; Burk, Diana C; Shahsavarani, Somayeh; Gonzalez-Castillo, Javier; Bandettini, Peter A.
Affiliation
  • Kronemer SI; Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland (MD), United States of America (USA).
  • Gobo VE; Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland (MD), United States of America (USA).
  • Walsh CR; Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland (MD), United States of America (USA).
  • Teves JB; Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland (MD), United States of America (USA).
  • Burk DC; Laboratory of Neuropsychology, NIMH, NIH, Bethesda, MD, USA.
  • Shahsavarani S; Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland (MD), United States of America (USA).
  • Gonzalez-Castillo J; Mortimer B. Zuckerman Mind Brain Behavior Institute and Department of Biomedical Engineering, Columbia, University, New York (NY), NY, USA.
  • Bandettini PA; Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland (MD), United States of America (USA).
bioRxiv ; 2024 Aug 13.
Article in En | MEDLINE | ID: mdl-38410482
ABSTRACT
Pupillometry is a popular method because pupil size is easily measured, sensitive to central neural activity, and associated with behavior, cognition, emotion, and perception. Currently, there is no method for online monitoring phases of pupil size fluctuation. We introduce rtPupilPhase - an open source software that automatically detects trends in pupil size in real time, enabling novel implementations of real time pupillometry towards achieving numerous research and translational goals. We validated the performance of rtPupilPhase on human, rodent, and monkey pupil data and propose future applications of real time pupillometry.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Document type: Article Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Document type: Article Country of publication: Estados Unidos