A Fe(III) intercalated clay nanoplatform for combined chemo/chemodynamic therapy.

Chen, Ying; Zhai, Jing; Wei, Shiqi; Tang, Aidong; Yang, Huaming

Chen, Ying; Zhai, Jing; Wei, Shiqi; Tang, Aidong; Yang, Huaming.

Affiliation

Chen Y; Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, China. tangaidong@cug.edu.cn.
Zhai J; Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China.
Wei S; Laboratory of Advanced Mineral Materials, China University of Geosciences, Wuhan 430074, China.
Tang A; Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, China. tangaidong@cug.edu.cn.
Yang H; Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China.

Chem Commun (Camb) ; 60(26): 3535-3538, 2024 Mar 26.

Article in En | MEDLINE | ID: mdl-38450703

ABSTRACT

ABSTRACT

A Fe(III) intercalated montmorillonite nanoplatform (Fe-MMT) was engineered for doxorubicin (DOX) loading. The constructed Fe-MMT/DOX nanoplatform could not only improve the production of H2O2 to enhance chemodynamic therapy but interfere with DNA damage repair to amplify the efficacy of DOX, proving an ideal combination of chemotherapy and chemodynamic therapy.

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ferric Compounds / Neoplasms Limits: Humans Language: En Journal: Chem Commun (Camb) / Chem. commun. (Lond., 1996, Online) / Chemical communications (London. 1996. Online) Journal subject: QUIMICA Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido

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