A 15% Trichloroacetic Acid + 3% Glycolic Acid Chemical Peel Series Improves Appearance of Hand Lentigines: An Evaluator-Blinded, Split-Hand Prospective Trial.
Dermatol Surg
; 50(5): 467-470, 2024 May 01.
Article
in En
| MEDLINE
| ID: mdl-38460193
ABSTRACT
BACKGROUND:
Improving the appearance of lentigines on the hands is a key component to hand rejuvenation. Soft tissue fillers revolumize hands, but do not address pigmentary changes.OBJECTIVE:
This study investigated the effiacy of a 15% trichloroacetic acid (TCA) + 3% glycolic acid (GA) combination peel in improvement of appearance of hand lentigines.METHODS:
A prospective evaluator-blinded, split-hand study was performed using a 15% TCA + 3% GA peel to treat patients with hand lentigines. Subjects received a total of 3 treatments at 4-week intervals on 1 hand, with the other hand serving as an untreated control. Final photographs were taken 12 weeks after the last treatment. Two blinded board-certified dermatologists graded improvement in hand lentigines using a 5-point scale.RESULTS:
Eighteen of 20 patients completed the study (90%). The mean age was 64.4 years (SE 1.6, range 51-71). The mean pain scores were 3.8 (SE 0.4) on a 10-point scale (1 = no pain, 10 = extremely painful). Blinded evaluators correctly identified the after-treatment photographs in 16 patients (88%). Physician and patient-graded mean improvement of lentigines was significant for treated versus control hands ( p < .01). No adverse events were noted.CONCLUSION:
A series of three 15% TCA + 3% GA peels are effective and safe in the treatment of hand lentigines.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Trichloroacetic Acid
/
Chemexfoliation
/
Glycolates
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Dermatol Surg
/
Dermatol. surg
/
Dermatologic surgery
Journal subject:
DERMATOLOGIA
Year:
2024
Document type:
Article
Country of publication:
Estados Unidos