Temperature management in acute brain injury: A narrative review.
Med Intensiva (Engl Ed)
; 48(6): 341-355, 2024 06.
Article
in En
| MEDLINE
| ID: mdl-38493062
ABSTRACT
Temperature management has been used in patients with acute brain injury resulting from different conditions, such as post-cardiac arrest hypoxic-ischaemic insult, acute ischaemic stroke, and severe traumatic brain injury. However, current evidence offers inconsistent and often contradictory results regarding the clinical benefit of this therapeutic strategy on mortality and functional outcomes. Current guidelines have focused mainly on active prevention and treatment of fever, while therapeutic hypothermia (TH) has fallen into disuse, although doubts persist as to its effectiveness according to the method of application and appropriate patient selection. This narrative review presents the most relevant clinical evidence on the effects of TH in patients with acute neurological damage, and the pathophysiological concepts supporting its use.
Key words
Accidente cerebro vascular isquémico agudo; Acute brain injury; Acute ischemic stroke; Brain hypoxia-ischemia; Control selectivo de la temperatura; Daño cerebral agudo; Encefalopatía hipóxico-isquémica; Hipotermia inducida; Hipotermia terapéutica; Hipoxia-isquemia cerebral; Hypoxic-ischemic encephalopathy; Induced hypothermia; Lesión cerebral aguda; Postcardiac arrest syndrome; Síndrome postparada cardiaca; Targeted temperature management; Therapeutic hypothermia; Traumatic brain injury; Traumatismo craneoencefálico
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain Injuries
/
Hypothermia, Induced
Limits:
Humans
Language:
En
Journal:
Med Intensiva (Engl Ed)
Year:
2024
Document type:
Article