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Brincidofovir for disease progression due to suspected tecovirimat resistance in association with advanced HIV.
Harrison, Iris; DeSear, Kathryn; Santevecchi, Barbara A; Venugopalan, Veena; Cherabuddi, Kartikeya; Iovine, Nicole; Radhakrishnan, Nila.
Affiliation
  • Harrison I; University of Florida College of Medicine, Gainesville, FL, USA.
  • DeSear K; Department of Pharmacy, University of Florida Health, Gainesville, FL, USA.
  • Santevecchi BA; Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL, USA.
  • Venugopalan V; Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL, USA.
  • Cherabuddi K; Division of Infectious Diseases & Global Medicine, University of Florida Health, Gainesville, FL, USA.
  • Iovine N; Division of Infectious Diseases & Global Medicine, University of Florida Health, Gainesville, FL, USA.
  • Radhakrishnan N; Department of Medicine, University of Florida Health, Gainesville, FL, USA.
Int J STD AIDS ; 35(8): 651-653, 2024 Jul.
Article in En | MEDLINE | ID: mdl-38502040
ABSTRACT
A man with advanced HIV presented with verrucous plaques 2-3 months after initial mpox infection. He received two courses of tecovirimat without resolution of initial mpox lesions and development of new lesions raising concern for resistance. He was treated with two doses of brincidofovir and demonstrated improvement 6 months later.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Disease Progression / Cytosine / Drug Resistance, Viral / Organophosphonates Limits: Humans / Male Language: En Journal: Int J STD AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Disease Progression / Cytosine / Drug Resistance, Viral / Organophosphonates Limits: Humans / Male Language: En Journal: Int J STD AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2024 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido