Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders.
Fukushima J Med Sci
; 2024 Mar 22.
Article
in En
| MEDLINE
| ID: mdl-38522893
ABSTRACT
BACKGROUND:
This study investigated changes of lipid parameters in children with severe eating disorders during refeeding in order to explore the optimal timing for lipid preparation administration.METHODS:
We prospectively assessed the physical conditions of patients with eating disorders after the start of nutrition therapy. The assessments were performed at admission and at 2 and 4 weeks. Lipid metabolism was assessed based on triglyceride (TG), total cholesterol (TC), and free carnitine (FC) levels, as well as acylcarnitine/free carnitine (AC/FC) ratio.RESULTS:
A total of 18 patients were included. Of these, 12 and 6 received an oral diet (OD group) and total parenteral nutrition (TPN group), respectively. The mean body mass indexes at hospital admission were 12.8 kg/m2 in the OD group and 12.7 kg/m2 in the TPN group. At 2 weeks after the start of refeeding, TC, TG, and AC/FC levels were significantly lower in the TPN group than in the OD group. Other blood test results did not show any significant differences between the two groups.CONCLUSIONS:
Fat-free glucose-based nutrition promoted lipid metabolism over a 2-week period after the start of refeeding, suggesting that balanced energy and lipid intake are essential, even in TPN.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Fukushima J Med Sci
Year:
2024
Document type:
Article
Country of publication:
Japón