Delivering synaptic protein mRNAs via extracellular vesicles ameliorates cognitive impairment in a mouse model of Alzheimer's disease.

Cai, Huimin; Pang, Yana; Ren, Ziye; Fu, Xiaofeng; Jia, Longfei

Cai, Huimin; Pang, Yana; Ren, Ziye; Fu, Xiaofeng; Jia, Longfei.

Affiliation

Cai H; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, 45 Changchun St., Beijing, 100053, China.
Pang Y; Center of Alzheimer's Disease, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China.
Ren Z; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, 45 Changchun St., Beijing, 100053, China.
Fu X; Center of Alzheimer's Disease, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China.
Jia L; Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, 45 Changchun St., Beijing, 100053, China.

BMC Med ; 22(1): 138, 2024 Mar 25.

Article in En | MEDLINE | ID: mdl-38528511

Subject(s)
Key words

Alzheimer's disease; Extracellular vesicles; Growth-associated protein 43; Messenger RNAs; Synaptic dysfunction; Synaptosome-associated protein 25

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease / Cognitive Dysfunction / Extracellular Vesicles Limits: Animals / Humans Language: En Journal: BMC Med Journal subject: MEDICINA Year: 2024 Document type: Article Affiliation country: China Country of publication: Reino Unido

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