[Survival analysis of 37 cases of malignant mesothelioma].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 42(3): 191-195, 2024 Mar 20.
Article
in Zh
| MEDLINE
| ID: mdl-38538239
ABSTRACT
Objective:
To explore the relationship between clinicopathological features, treatment and prognosis of patients with malignant mesothelioma, and provide theoretical basis for the prevention and treatment of malignant mesothelioma.Methods:
In November 2022, the clinical data of 37 patients with malignant mesothelioma diagnosed in Qingdao Central Hospital from July 2014 to November 2022 were retrospectively analyzed, and the prognostic factors were analyzed by Kaplan-Meier and log-rank tests.Results:
The median age of the 37 patients was 66 years old, all patients were confirmed by pathology. The median survival time of all patients was 30.00 months. The 1-year, 2-year, 3-year and 5-year cumulative survival rates were 70.27% (26/37), 48.65% (18/37), 16.22% (6/37) and 13.51% (5/37), respectively. Compared with different treatments, the median survival time of palliative care patients was 5.00 months, which was significantly lower than that of operation group (30.33 months), chemotherapy group (30.00 months), surgery combined with chemotherapy group (30.00 months) and chemotherapy combined with bevacizumab targeted therapy group (47.42 months) (P<0.05). Gender, age (≥60 years old or <60 years old), smoking history, occupational exposure history, disease site, and surgical history were not factors affecting the survival of malignant mesothelioma patients (P>0.05) .Conclusion:
The clinical symptoms of malignant mesothelioma are not specific, but early initiation of treatment can still prolong survival, and chemotherapy combined with anti-vascular targeted therapy shows better therapeutic effect.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pleural Neoplasms
/
Mesothelioma, Malignant
/
Lung Neoplasms
/
Mesothelioma
Limits:
Aged
/
Humans
/
Middle aged
Language:
Zh
Journal:
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Journal subject:
MEDICINA OCUPACIONAL
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
China