Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose-Derived Triol Monomer: A Design of Experiment Approach.
ChemSusChem
; 17(11): e202301841, 2024 Jun 10.
Article
in En
| MEDLINE
| ID: mdl-38545821
ABSTRACT
Regioselective enzymatic polycondensation of the bio-based cellulose derived polyol, Triol-citro, and dimethyl adipate using Candida antarctica Lipaseâ
B (CaLB) was investigated. A Design of Experiment approach with MODDE® Pro 13 was used to determine important factors in the branching behavior of this polymer, and reactant ratio, temperature, reaction time and enzyme wt % were the studied factors. Multifunctional polyesters with pendant hydroxy groups were synthesized and fully characterized using 2D NMR techniques to determine degree of branching. Branching was minimal, with a maximum of 16 % observed, and monomer ratio, temperature and reaction time were all determined to be significant factors. In this work, Mn of up to 13â
kDa were achieved, while maintaining degree of branching below 15 %, resulting in a linear polyester with the potential to be further functionalized.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polyesters
/
Fungal Proteins
/
Cellulose
/
Lipase
Language:
En
Journal:
ChemSusChem
/
ChemSusChem (Weinh., Internet)
/
ChemSusChem (Weinheim. Internet)
Journal subject:
QUIMICA
/
TOXICOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Austria
Country of publication:
Alemania