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Impact of metagenomic next-generation sequencing on clinical decision-making at an academic medical center, a retrospective study, Iowa, 2020-2022.
Olthoff, Michael; Kobayashi, Takaaki; Parsons, Meredith G; Ford, Bradley; Prasidthrathsint, Kunatum; Non, Lemuel; Salinas, Jorge L; Diekema, Daniel J; Ince, Dilek.
Affiliation
  • Olthoff M; Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Kobayashi T; Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Parsons MG; Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Ford B; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Prasidthrathsint K; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Non L; Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Salinas JL; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Diekema DJ; Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
  • Ince D; Department of Internal Medicine, Stanford University, Stanford, CA, USA.
Article in En | MEDLINE | ID: mdl-38562514
ABSTRACT
We assessed the impact of metagenomic next-generation sequencing (mNGS) on patient care using previously established criteria. Among 37 patients receiving mNGS testing, 16% showed results that had a positive clinical impact. While mNGS results may offer valuable supplementary information, results should be interpreted within the broader clinical context and evaluation.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Antimicrob Steward Healthc Epidemiol Year: 2024 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Antimicrob Steward Healthc Epidemiol Year: 2024 Document type: Article Affiliation country: Estados Unidos